Incorporation of Pharmacokinetic and Pharmacodynamic Data into Risk Assessments
نویسندگان
چکیده
منابع مشابه
Incorporation of pharmacokinetic and pharmacodynamic data into risk assessments.
Risk assessment methodologies are being updated to allow the inclusion of numerical values for variance in pharmacokinetic (PK) measures and pharmacodynamic (PD) processes related to toxicity. The key PK measures and PD processes are identified from the results of carefully conducted and adequately reported studies. In some instances, studies with humans are not possible, and so the development...
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ژورنال
عنوان ژورنال: Toxicology Mechanisms and Methods
سال: 2004
ISSN: 1537-6516,1537-6524
DOI: 10.1080/15376520490429382